The Pittsburgh Science of Learning Center is leveraging computational theory and cognitive modeling to identify the instructional conditions that cause robust student learning. PSLC has created the Learnlab facility designed to dramatically increase the ease and speed with which learning researchers can create the rigorous, course-based experiments that pave the way to an understanding of robust learning. The Center is cross-organized by four research thrusts (Cognitive Factors, Metacognition and Motivation, Social Communicative Factors, Computational Modeling and Data Mining) and six LearnLab courses (Algebra, Geometry, Chemistry, Physics, Chinese, and English as a Second Language).